Word: SIS

The word SIS has appeared in at least 407 clues on different crosswords.

Clue(s)
Sue Grafton's "___ for Silence"
Uses a keyhole, perhaps
Certain sib
Bro? No, the other
Bro's kin
A sib, for short
Female sibling, for short
Girl of the fam, for short
Bro's sib
Family gal
Bro's kin
Girl of the fam
Mom, to Auntie
Family gal, briefly
Lisa Simpson, to Bart
Family nickname
A sib
Bro's sibling
Certain sib
Short sibling?
Nickname for a female sibling
Start of a cheer
Girl sibling, for short
Family nickname
Bro's kin
Start of a cry that ends "bah!"
Marcia, to Greg
Palindromic relative
Female relative
Auntie, to one's parent
Cheer starter
Venus, to Serena
Family girl, briefly
Female relative
Venus, to Serena
Bro's sibling
Sib
Family nickname
Family moniker
Bro's sibling
Certain sib
Family nickname
Relative, for short
Family nickname
Household name?
Marie, to Donny
10-Across sibling
Venus, to Serena
Affirmatives, to Pancho
Relative, for short
Bro's twin
Bro's counterpart
Kate to Ashley
Bro's pal
54-Across' sib
Bro's partner
Bro's sibling
Female sibling, for short
Bro's pal
Female sib.
Venus, to Serena
"Rah, rah, ___-boom-bah!"
Your aunt would be one, but not your bro
A sib, for short
Certain sib
Pop's daughter
Female sibling, for short
Sibling
''__ for Silence'' (Grafton novel)
Family nickname
Female version of "bro"
"___-boom-bah!"
Marie, to Donny
Family gal
Bro's kin
Female sibling, for short
Female sibling, for short
Brother's sibling, for short
Bro's counterpart
Tina Belcher, to Gene, on "Bob's Burgers"
Bro's sib
One relatively close either way?
Ann, to Abby
Bro's sibling
Girl of the fam, for short
Serena, to Venus
Bro's female counterpart
Nickname for a female sibling
Palindromic nickname
Bro's sibling
Bro's counterpart
Bro's sibling
Girl with the same mother, briefly
Bro's sibling, for short
Close relative
Pop's daughter
Familial sobriquet
Family member, for short
Amy, to Meg and Beth in "Little Women," for short
Female sibling, for short
Venus, to Serena
Ivanka Trump, to Eric Trump
A sib
Bro's sib
Sibling
"Rah, rah, ___-boom-bah!"
Bro's kin
Family nickname
Cheer starter
Start of a cheer
Family nickname
Bro's sibling
Family nickname
A sib
Close relative, briefly
A sib
Family nickname
Bro's rival, for short
Girl of the fam, for short
Family nickname
A sib
Family girl
Bro's sibling
Family nickname
Family mem.
Sib
La Toya, to Michael
One of the family
Term of address for a drag queen
Serena Williams, to Venus
Family nickname
Female sibling, for short
Sibling
Family nickname
Female version of "bro"
What your father might call your aunt
Female sibling, for short
Family nickname
Auntie, to Mom
Bro's counterpart
Family girl, briefly
Family member, for short
Sib
Family girl
Just one of the fam
Bro’s sibling
Palindromic relative
Household name
Bro’s sibling
Female relative
Close relative
Kate, to Randall and Kevin on "This Is Us," for short
Family girl
Short form of sister
Serena, to Venus
Female relative
See 1-Across
Bro's sibling
Spanish yeses
Female sibling, for short
A sib, briefly
Sibling, for short
Kim Kardashian West, to Kourtney Kardashian
Bro’s sib
Close relative
Family member, for short
Bro's sibling
Brother's sibling, for short
Bro's sibling, briefly
Meg, to Chris and Stewie, on "Family Guy"
"Rah, rah, ___-boom-bah!"
Nickname for a female sibling
"Revenge of the ___" ("Star Wars: Jedi Academy" book)
Female sibling, for short
Affirmatives, to Pancho
Girl of the family, for short
"___ boom bah!"
Female relative
Bro counterpart
Sib
Family nickname
Lisa Simpson, to Bart
Girl's nickname
Bro’s counterpart
Family nickname
Sibling, for short
Female sibling, for short
Auntie, to Mom
Female sib
Female child to another, for short
Ann, to Abby
Bro's sib
Family nickname
Bro's pal
Family nickname
What Kim might call Khloé
Certain sib
Female in the fam
Female counterpart of "bro"
Relative's nickname
Member of the fam
Bro's female sibling, for short
Family girl
Certain sib
Female sibling, for short
"___ boom bah!"
A sib
Relative's nickname
A sib, for short
Shirley MacLaine, to Warren Beatty
Female family member (briefly)`
Kourtney, to Kim
Auntie, to Mom
Family gal, briefly
Malia Obama, to Sasha
Bro's relative
Female sibling's nickname
Female sibling, for short
Sibling
Part of the fam
Sibling
Girl sibling, for short
Marcia, to Greg
"___ boom bah!"
Female relative
Bro's sibling
Family nickname
Family girl, briefly
Girl of the family, for short
Female relative
Bro's sibling
Kin
What Khloe might call Kim
Your aunt would be one, but not your bro
Mom's daughter
Family nickname
Sibling
Sib
Close relative
Female sibling, for short
Female version of "bro"
Bro's sibling
Bro's partner
Bro's sibling
Member of the fam
Bro's sibling, for short
Marie, to Donny
Bro's sib
Affirmatives, to Pancho
Charlie had two bros and a ___
Bro's sib
"Rah, rah, ___-boom-bah!"
Bro's pal
Family nickname
Your aunt would be one, but not your bro
Bro's sibling
Spanish yeses
Start of a cheer
Bro's pal
Familial comrade
Emily Deschanel's relationship to Zooey, for short
A sib, for short
Sonny's sib
Member of the fam
Family girl
Familial nickname
Female sibling, for short
Some votes in Venezuela
Female sibling, for short
Amy, to Meg or Beth in "Little Women," for short
Serena to Venus, for short
Ann, to Abby
Female sibling, for short
Bro's sibling
Palindromic term of address
What the Olsen twins might call each other
Maggie Gyllenhaal, to Jake Gyllenhaal
Sibling
YouTube's ___ vs. BRO
Bro's counterpart
Family member, for short
Female sibling, for short
"___ for Silence" (Sue Grafton mystery): 2 wds.
Relative's nickname
Fam girl
Girl of the fam, for short
___ Got Tea (Louisville tea shop)
"___ boom bah!"
Member of the fam
Family girl
What your mother might call your aunt
What Khloe might call Kim
Willow, to Jaden, for short
Certain sib
Solange, to Beyonce, for short
Palindromic sib
Bro's sibling
Relative's nickname
Female person who has the same parents as another person
Female family member (briefly)`
Bro's sib, maybe
Member of the fam
Auntie, to Mom
14-Across to Danielle and Alana
Bro's rival, for short
Softball star Bates
"Rah, rah, ___-boom-bah!"
Sally, to Charlie Brown
Bey, to Solange
Member of the fam
Bro's sibling
Elle Fanning, to Dakota Fanning
Sib
Female sibling, for short
Tegan, to Sara, for short
Palindromic sibling
Sib's nickname
Spanish yeses
Close relative
Girl with the same mother, briefly
Bro's counterpart
Bella, to Gigi, for short
A sib
"Go Off, ___" (podcast)
Girl of the fam, for short
Bro's counterpart
Family girl, briefly
Family member, for short
Sib
Palindromic sib
Female sibling, for short
Actress who organized the Trans March on Broadway in 2021
Sib's nickname
Palindromic relative
Female relative
Female counterpart of "bro"
Solange, to Beyoncé
Bro's kin
Your aunt would be one, but not your bro
Girl sibling, briefly
Nuclear unit nickname
Female relative
Beyoncé, to Solange, informally
A sib, briefly
Sibling, for short
Girl's nickname
"___ boom bah!"
Bro's sibling
Family member, for short
Bro's sibling, briefly
Lil ___ (two-palindrome family member)
"Rah, rah, ___-boom-bah!"
Solange, to Beyonce, informally
Bro's sib, perhaps
Relative, for short
Affirmatives, to Pancho
Female sibling's nickname
Serena, to Venus, for shortend
Certain sib
Family girl, informally
Female relative
What Serena Williams might call Venus Williams
Cheer starter
Chloe, to Halle, for short
Frequent maid of honor, in brief
Bro's relative
Sib
Lisa Simpson, to Bart
Sibling nickname
Tamera, to Tia, for short
Girl of the fam, for short
First roomie, maybe
Female sibling, for short
Family gal
Sibling, for short
Female sib
What your aunt might call your mother
Relative's nickname
Bro's sib
Member of the fam
Relative, for short
Ann, to Abby
Female equivalent of "bro"
Lilo, to Nani, for short
What Solange might call Beyoncé
Sibling nickname
Bro's pal
Certain sib
Palindromic sib
Kim, to Khloe or Kourtney, informally
Certain sib
A sib, for short
Sibling
"___ boom bah!"
Female sibling, for short
"___ boom bah!"
Auntie, to mom
Family gal, briefly
Family mem.
Close relative
Girl of the fam, for short
Member of the fam
Family mem.
Sobriquet for a sibling
Bro's sibling
Aunt, to Mom
Sibling