Mind-altering drug

The clue "Mind-altering drug" was last spotted by us at the USA Today Crossword on May 9 2019.

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We found 1 possible solution for the Mind-altering drug clue.

Possible Solution

O P I A T E

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USA Today Clues May 09, 2019

Handy sources of cash
Sidesplitter
Skunk’s giveaway
Made do
On the same side
Home care pro
Mountaineer's stop
Song in a libretto
President after Madison
"Lust, Caution" director Lee
Jazz club get-together
Home to much of the Silk Road
"Didn't hear you"
Lacking a key
Diet brand word
Like petting-zoo animals
Munich ___ of 1938
Femmes fatales
For all to see
Fearsome striped fish
Like a spoiled kid
Bathtub murder victim of 1793
Poet's muse
Energy Star org.
Haagen-Dazs holder
Rational thinking
Hunter's quarry
Barely adequate
DNA map
Easy infield chances
Handy bags
Surveyor's finding
Wound remnant
Guantanamo locale
"Mamma Mia!" group
22-Across part
Russian-born deco designer
One squat, say
Versifier's "before"end
Cinnabon stand come-on
Andean wool source
Uppercut target
Like pools on a beach
Eva or Juan in "Evita"
Kilauea output
Apollo program feat
Hamm of soccer
Waterway named for Bering
Fish with a long 11-Across
Aspiring JD's exam
Crystal-filled rock
Mayberry tyke
Was a naysayer
"I'm clueless!"
Keen, as a sports buff
Taiwanese PC giant
Labor activist Chavez
One of the Little Women
Ready-made PC images
The lyrical Gershwin
Pasta sauce brand
Having missed the boat
Castle defense
Off the wall
Draw upon
Member of Hook's crew
Big name in chicken
Arthur on a U.S. stamp
Sgt., e.g.
Mind-altering drug
Smart TV brand
66, historically
Audiologist's concern
Bonfire remnant
Blue Ribbon beer
Couples-carrying craft
Spherical veggies, in rhyme
Election day list